Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659654 | 0.94 | GAA (0.56) | GAAFFAR1POLBTNF | |
| SCHEMBL3655663 | 0.94 | GAA (0.56) | GAAFFAR1POLBTNF | |
| SCHEMBL2499134 | 0.90 | GAA (0.52) | GAAFFAR1POLB | |
| SCHEMBL2497911 | 0.90 | GAA (0.52) | GAAFFAR1POLB | |
| SCHEMBL20379539 | 0.88 | FFAR1 (0.57) | GAAFFAR1POLBTNFCTSA | |
| SCHEMBL2499131 | 0.81 | PDE4A (0.47) | GAATNF | |
| SCHEMBL2497909 | 0.81 | PDE4A (0.47) | GAATNF | |
| SCHEMBL16319202 | 0.80 | FFAR1 (0.52) | FFAR1 | |
| SCHEMBL20379832 | 0.80 | FFAR1 (0.51) | GAAFFAR1POLBCTSA | |
| SCHEMBL20379833 | 0.80 | FFAR1 (0.51) | GAAFFAR1POLBCTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058254-A1 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |