Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497911 | 1.00 | GAA (0.52) | GAAFFAR1TAS1R3TAS1R1POLB | |
| SCHEMBL3655663 | 0.90 | GAA (0.56) | GAAFFAR1POLB | |
| SCHEMBL3659654 | 0.90 | GAA (0.56) | GAAFFAR1POLB | |
| SCHEMBL8337209 | 0.90 | GAA (0.58) | GAAFFAR1POLB | |
| SCHEMBL19003549 | 0.85 | TAS1R3 (0.40) | TAS1R3TAS1R1 | |
| SCHEMBL2503228 | 0.85 | GAA (0.53) | GAAFFAR1TAS1R3TAS1R1POLB | |
| SCHEMBL2497024 | 0.85 | GAA (0.53) | GAAFFAR1TAS1R3TAS1R1POLB | |
| SCHEMBL20372911 | 0.84 | TAS1R3 (0.40) | TAS1R3TAS1R1 | |
| SCHEMBL2501254 | 0.82 | ADRB1 (0.43) | GAAFFAR1 | |
| SCHEMBL2495292 | 0.82 | ADRB1 (0.43) | GAAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030354-B2 | 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes | AMGEN INC. (US) | 2011-10-04 | — | — | US | disclosed |