Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926415 | 0.90 | ALB (0.55) | KDM4EALDH1A1MEN1USP2DHFR | |
| SCHEMBL4831777 | 0.90 | CDK2 (0.55) | KDM4EALDH1A1CDK2HDAC1HDAC6 | |
| SCHEMBL4831785 | 0.90 | CDK2 (0.55) | KDM4EALDH1A1CDK2HDAC1HDAC6 | |
| SCHEMBL5926546 | 0.89 | MMEL1 (0.49) | KDM4EALDH1A1CDK2HDAC1HDAC6 | |
| SCHEMBL4831913 | 0.88 | CDK2 (0.53) | KDM4EALDH1A1CDK2HDAC1HDAC6 | |
| SCHEMBL4829786 | 0.87 | CDK2 (0.59) | KDM4EALDH1A1CDK2HDAC1HDAC6 | |
| SCHEMBL4829792 | 0.87 | CDK2 (0.59) | KDM4EALDH1A1CDK2HDAC1HDAC6 | |
| SCHEMBL4829649 | 0.86 | CDK2 (0.53) | KDM4EALDH1A1CDK2HDAC1HDAC6 | |
| SCHEMBL5926398 | 0.84 | CDK2 (0.52) | KDM4EALDH1A1KMT2ACDK2HDAC1 | |
| SCHEMBL6401251 | 0.84 | CDK2 (0.51) | KDM4EALDH1A1CDK2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |