SCHEMBL8337259

SCHEMBL8337259

CNC(C)CN1CCN(C)CC1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
KDM4E B2RXH2 2/20 0.37
GLA P06280 1/20 0.37
OGA O60502 1/20 0.37
POLB P06746 1/20 0.35
TSHR P16473 2/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
USP2 O75604 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 2/20 0.33
PIK3CD O00329 1/20 0.32
MC4R P32245 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9511251 0.81 KMT2A (0.42) MAPTALDH1A1SIGMAR1
SCHEMBL9511248 0.81 KMT2A (0.42) MAPTALDH1A1SIGMAR1
SCHEMBL7342935 0.81 KMT2A (0.42) MAPTALDH1A1SIGMAR1
SCHEMBL28642601 0.80 PAOX (0.33) GAAKDM4ESMN1; SMN2ALDH1A1MC4R
SCHEMBL17424103 0.79 MEN1 (0.46) MAPTALDH1A1SIGMAR1
SCHEMBL25575441 0.79 MEN1 (0.46) MAPTALDH1A1SIGMAR1
SCHEMBL14473037 0.78 GAA (0.37) GAAKDM4EGLAOGAPOLB
SCHEMBL8071370 0.77 PAOX (0.39) MAPTUSP2SMN1; SMN2ALDH1A1SIGMAR1
SCHEMBL16349983 0.77 KMT2A (0.37) ALDH1A1
SCHEMBL19919871 0.76 USP2 (0.50) KDM4EMAPTL3MBTL1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113453784-B Method for removing acid gases from fluid streams 巴斯夫欧洲公司 2024-09-13 CN disclosed
WO-2023205680-A1 PI3Kα INHIBITORS SYNNOVATION THERAPEUTICS, INC. (US) 2023-10-26 WO disclosed
CN-113453784-A Process for removing acid gases from fluid streams 巴斯夫欧洲公司 2021-09-28 CN disclosed
EP-2448654-B1 ACID GAS SCRUBBING COMPOSITION NALCO CO (US) 2019-05-01 EP disclosed
WO-2004024728-A2 PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-03-25 WO disclosed