Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531865 | 0.79 | PIK3CD (0.47) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL26352153 | 0.78 | MEN1 (0.33) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL8337259 | 0.77 | GAA (0.39) | ALDH1A1 | |
| SCHEMBL9511248 | 0.76 | KMT2A (0.42) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7342935 | 0.76 | KMT2A (0.42) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL9511251 | 0.76 | KMT2A (0.42) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL24615932 | 0.75 | RAB9A (0.41) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL7145573 | 0.75 | RAB9A (0.41) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL7604180 | 0.75 | KMT2A (0.39) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL24481424 | 0.75 | KMT2A (0.39) | KMT2AMEN1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342037-B2 | Anti-inflammatory medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-03-11 | — | — | US | disclosed |