Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.43 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333978 | 0.88 | RAD52 (0.42) | MAPTKDM4ELMNAGRIA1CACNG8 | |
| SCHEMBL6844237 | 0.75 | TSHR (0.56) | MAPTKDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL27952100 | 0.71 | ALDH1A1 (0.69) | MAPTKDM4ELMNAGRIA1CACNG8 | |
| SCHEMBL4305298 | 0.68 | GRM2 (0.58) | MAPTKDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL2607467 | 0.68 | ALDH1A1 (0.72) | MAPTKDM4ELMNAL3MBTL1KMT2A | |
| SCHEMBL6839523 | 0.68 | MAPT (0.57) | MAPTKDM4ELMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8021989 | 0.66 | KDM4E (0.48) | MAPTKDM4ELMNAKMT2AMEN1 | |
| SCHEMBL9694043 | 0.65 | HSD17B10 (0.52) | MAPTKDM4ELMNAL3MBTL1KMT2A | |
| SCHEMBL13033400 | 0.64 | SMO (0.46) | KDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8027446 | 0.64 | KDM4E (0.61) | MAPTKDM4ELMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889010-A | PSYCHOLOGICAL DISORDERS; UROGENITAL DISORDERS; COGNITION ACTIVATORS; NERVOUS SYSTEM DISORDERS; VISION DEFECTS; CONGESTIVE HEART FAILURE; DRUG ABRUSE; PARKINSON'S DISEASE;ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | PFIZER INC. (US) | 1999-03-30 | — | — | US | disclosed |