Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337215 | 1.00 | REN (0.66) | RENKDM1AMAOAMAOB | |
| SCHEMBL8338398 | 0.93 | REN (0.69) | RENKDM1AMAOAMAOB | |
| SCHEMBL8338489 | 0.93 | REN (0.69) | RENKDM1AMAOAMAOB | |
| SCHEMBL8337973 | 0.84 | REN (0.67) | RENKDM1AMAOAMAOB | |
| SCHEMBL8338374 | 0.84 | REN (0.67) | RENKDM1AMAOAMAOB | |
| SCHEMBL5777293 | 0.84 | REN (0.67) | RENKDM1AMAOAMAOB | |
| SCHEMBL8339031 | 0.84 | REN (0.83) | REN | |
| SCHEMBL8339706 | 0.84 | REN (0.83) | REN | |
| SCHEMBL8339861 | 0.83 | REN (0.63) | RENKDM1AMAOAMAOB | |
| SCHEMBL5801143 | 0.83 | REN (0.63) | RENKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089903-A9 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER LAMBERT CO (US) | 2005-10-27 | — | — | WO | disclosed |