Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 16/20 | 0.44 |
| ▸ | GALR1 | P47211 | 5/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246418 | 0.76 | GALR2 (0.44) | GALR2GALR1AURKARIPK1AURKB | |
| SCHEMBL3245944 | 0.74 | SLC29A1 (0.48) | GALR2GALR1APAF1GAAMAPT | |
| SCHEMBL3245932 | 0.71 | GALR2 (0.61) | GALR2GALR1APAF1GAAMAPT | |
| SCHEMBL3242653 | 0.70 | GALR2 (0.45) | GALR2GALR1AURKARIPK1AURKB | |
| SCHEMBL10143556 | 0.69 | GALR2 (0.80) | GALR2GALR1AURKA | |
| SCHEMBL3244088 | 0.67 | GALR2 (0.62) | GALR2GALR1AURKARIPK1AURKB | |
| SCHEMBL10143740 | 0.67 | GALR2 (0.67) | GALR2GALR1 | |
| SCHEMBL3247402 | 0.67 | GALR2 (0.62) | GALR2GALR1AURKARIPK1AURKB | |
| SCHEMBL3240506 | 0.66 | GALR2 (0.48) | GALR2GALR1APAF1GAAMAPT | |
| SCHEMBL3246321 | 0.66 | CASP1 (0.59) | GALR2GALR1APAF1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014376-A1 | GAL3 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF AFFECTIVE DISORDERS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-02-19 | — | — | WO | disclosed |