Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.56 |
| ▸ | RXRG | P48443 | 11/20 | 0.56 |
| ▸ | RXRB | P28702 | 11/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12646504 | 0.88 | MAOB (0.57) | BACE1FFAR1 | |
| SCHEMBL4974901 | 0.85 | TACR1 (0.43) | — | |
| SCHEMBL853787 | 0.85 | FFAR1 (0.54) | HRH3HDAC1FFAR1 | |
| Hydrochloric Acid SCHEMBL4974896 | 0.83 | IDO1 (0.43) | — | |
| SCHEMBL1841217 | 0.81 | HRH3 (0.49) | RXRARXRGRXRBHRH3HDAC1 | |
| Trifluoroacetic Acid SCHEMBL30151162 | 0.79 | FFAR1 (0.56) | HRH3HDAC1FFAR1 | |
| SCHEMBL12370802 | 0.79 | HRH3 (0.50) | RXRARXRGRXRBHRH3SYK | |
| SCHEMBL12370805 | 0.79 | SYK (0.50) | RXRARXRGRXRBHRH3SYK | |
| SCHEMBL8337953 | 0.79 | RXRA (0.55) | RXRARXRGRXRBBACE1BACE2 | |
| SCHEMBL1841248 | 0.79 | CYP11B1 (0.53) | HRH3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |