Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.49 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.49 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.47 |
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | CPA1 | P15085 | 4/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926666 | 1.00 | ITGB1 (0.54) | ITGB1ITGA4ITGB7PTPN1ERAP1 | |
| SCHEMBL5926539 | 0.91 | GPR34 (0.66) | PTPN1GPR34MMEACECPA1 | |
| SCHEMBL5926498 | 0.87 | ITGB1 (0.52) | ITGB1ITGA4ITGB7ERAP1GPR34 | |
| SCHEMBL5926536 | 0.86 | PTPN1 (0.52) | ITGB1ITGA4ITGB7PTPN1ERAP1 | |
| SCHEMBL5927188 | 0.86 | ITGB1 (0.52) | ITGB1ITGA4ITGB7PTPN1ERAP1 | |
| SCHEMBL5926531 | 0.85 | ITGB1 (0.51) | ITGB1ITGA4ITGB7PTPN1ERAP1 | |
| SCHEMBL5926681 | 0.83 | ERAP1 (0.53) | ITGB1ITGA4ITGB7ERAP1GPR34 | |
| SCHEMBL5926672 | 0.82 | ITGB1 (0.49) | ITGB1ITGA4ITGB7PTPN1ERAP1 | |
| SCHEMBL5927464 | 0.82 | ITGB1 (0.49) | ITGB1ITGA4ITGB7PTPN1ERAP1 | |
| SCHEMBL5926430 | 0.82 | ITGB1 (0.48) | ITGB1ITGA4ITGB7PTPN1ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |