Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.56 |
| ▸ | PYGL | P06737 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344791 | 1.00 | KMT2A (0.58) | KMT2ATSHRAAK1PYGLTAS1R3 | |
| SCHEMBL8346691 | 1.00 | KMT2A (0.58) | KMT2ATSHRAAK1PYGLTAS1R3 | |
| SCHEMBL38661620 | 0.88 | AAK1 (0.66) | KMT2ATSHRAAK1TAS1R3TAS1R1 | |
| SCHEMBL30807751 | 0.85 | AAK1 (0.53) | KMT2ATSHRAAK1MAPTREN | |
| SCHEMBL6824922 | 0.84 | KMT2A (0.63) | KMT2ATSHRPYGLTAS1R3TAS1R1 | |
| SCHEMBL28898095 | 0.82 | AAK1 (0.58) | KMT2ATSHRAAK1PYGLTAS1R3 | |
| SCHEMBL8337536 | 0.81 | HPN (0.58) | KMT2AAAK1MAPT | |
| SCHEMBL30807741 | 0.81 | AAK1 (0.54) | KMT2ATSHRAAK1MAPTL3MBTL1 | |
| SCHEMBL29231500 | 0.79 | AAK1 (0.52) | KMT2ATSHRAAK1PYGLTAS1R3 | |
| SCHEMBL30807770 | 0.78 | AAK1 (0.58) | KMT2ATSHRAAK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |