Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PYGL | P06737 | 4/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344791 | 0.84 | KMT2A (0.58) | KMT2ATSHRPYGLTAS1R3TAS1R1 | |
| SCHEMBL8346691 | 0.84 | KMT2A (0.58) | KMT2ATSHRPYGLTAS1R3TAS1R1 | |
| SCHEMBL8338013 | 0.84 | KMT2A (0.58) | KMT2ATSHRPYGLTAS1R3TAS1R1 | |
| SCHEMBL27143850 | 0.83 | HTR1E (0.60) | KMT2ATSHRPOLB | |
| SCHEMBL27143848 | 0.83 | HTR1E (0.60) | KMT2ATSHRPOLB | |
| SCHEMBL8334912 | 0.82 | KMT2A (0.53) | KMT2ATSHRPYGL | |
| SCHEMBL6723497 | 0.82 | KMT2A (0.67) | KMT2ATSHRPYGLTAS1R3TAS1R1 | |
| SCHEMBL6715815 | 0.82 | KMT2A (0.67) | KMT2ATSHRPYGLTAS1R3TAS1R1 | |
| SCHEMBL6715808 | 0.82 | KMT2A (0.67) | KMT2ATSHRPYGLTAS1R3TAS1R1 | |
| SCHEMBL6723568 | 0.79 | ALDH1A1 (0.51) | KMT2ATSHRPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |