Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796004 | 0.93 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDHTTALDH1A1ALPL | |
| SCHEMBL10432974 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDHTTALDH1A1ALPL | |
| SCHEMBL7802043 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDHTTALDH1A1ALPL | |
| SCHEMBL19223897 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTALDH1A1ALPL | |
| SCHEMBL16847503 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTALDH1A1ALPL | |
| SCHEMBL22834417 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDHTTALDH1A1ALPL | |
| SCHEMBL10432975 | 0.80 | MGLL (0.51) | SMN1; SMN2HPGDHTTALDH1A1GAA | |
| SCHEMBL31065087 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTALDH1A1ALPL | |
| SCHEMBL1618771 | 0.79 | PTGS1 (0.61) | SMN1; SMN2HPGDHTTALDH1A1ALPL | |
| SCHEMBL8763346 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDHTTALDH1A1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994284-A | REACTING PHTHALIC ACID OR ANHYDRIDE WITH CAPROLACTAM; OXIDATION WITH HYDROGEN PEROXIDE | CLARIANT GMBH (DE) | 1999-11-30 | — | — | US | disclosed |
| US-5061807-A | IMIDOPEROXYCARBOXYLIC ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |