⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614351 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL30852195 | 0.97 | — | — | |
| SCHEMBL29479476 | 0.72 | — | — | |
| SCHEMBL423090 | 0.72 | — | — | |
| SCHEMBL29770643 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL18227036 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL20338348 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL28430002 | 0.70 | — | — | |
| SCHEMBL2042798 | 0.70 | — | — | |
| SCHEMBL28537378 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072299-B1 | 4-METHYL-6-PHENYL-PYRIDAZINE DERIVATIVES ACTIVE ON THE CENTRAL NERVOUS SYSTEM | SANOFI S.A. (FR) | 1986-12-17 | — | — | EP | claimed |
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |
| CN-109790181-A | Bridging piperidine derivative | 豪夫迈·罗氏有限公司 | 2019-05-21 | — | — | CN | disclosed |
| US-20170065575-A1 | NAMPT INHIBITORS | ABBVIE INC (US) | 2017-03-09 | — | — | US | disclosed |
| US-9434721-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2016-09-06 | — | — | US | disclosed |
| US-20150141398-A1 | NAMPT INHIBITORS | ABBVIE INC. | 2015-05-21 | — | — | US | disclosed |
| CN-104583194-A | Pyridazine and pyridine derivatives as NAMPT inhibitors | ABBVIE INC | 2015-04-29 | — | — | CN | disclosed |
| EP-2847181-A1 | PYRIDAZINE AND PYRIDINE DERIVATIVES AS NAMPT INHIBITORS | AbbVie Inc. (US) | 2015-03-18 | — | — | EP | disclosed |
| US-8975398-B2 | NAMPT inhibitors | ABBVIE INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-20140142112-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8536177-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2013-09-17 | — | — | US | disclosed |
| US-7994167-B2 | Pentafluorosulphanyl-substituted compound and its use for producing medicaments | GRUENENTHAL GMBH (DE) | 2011-08-09 | — | — | US | disclosed |
| WO-2011050160-A1 | PHARMACEUTICALS, COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2011-04-28 | — | — | WO | disclosed |
| CN-101679405-A | 2-aminopyridine analogs as glucokinase activators | ARRAY BIOPHARMA INC | 2010-03-24 | — | — | CN | disclosed |
| US-7683063-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2010-03-23 | — | — | US | disclosed |
| US-20090137594-A1 | Pentafluorosulphanyl-Substituted Compound And Its Use For Producing Medicaments | GRUENENTHAL GMGH (DE) | 2009-05-28 | — | — | US | disclosed |
| US-7262194-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. | 2007-08-28 | — | — | US | disclosed |
| US-20070027159-A1 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. | 2007-02-01 | — | — | US | disclosed |
| WO-2004011441-A1 | PYRIDAZINYLPIPERAZINE DERIVATIVES FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2004-02-05 | — | — | WO | disclosed |
| EP-0072299-B1 | 4-METHYL-6-PHENYL-PYRIDAZINE DERIVATIVES ACTIVE ON THE CENTRAL NERVOUS SYSTEM | SANOFI S.A. (FR) | 1986-12-17 | — | — | EP | disclosed |