⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29131780 | 0.97 | NOS3 (0.32) | — | |
| SCHEMBL29770643 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28430002 | 0.94 | — | — | |
| Formamide SCHEMBL25308554 | 0.84 | NOS3 (0.32) | — | |
| SCHEMBL28909733 | 0.84 | — | — | |
| SCHEMBL28537378 | 0.82 | — | — | |
| SCHEMBL15004521 | 0.72 | — | — | |
| SCHEMBL3915380 | 0.70 | — | — | |
| SCHEMBL8338293 | 0.70 | — | — | |
| SCHEMBL6091759 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110691598-A | Metalloenzyme inhibitor compounds | 赛列尼蒂治疗(百慕大)有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-105793249-A | Piperidine derivatives for the treatment or prevention of psychiatric and neurological disorders | 武田药品工业株式会社 | 2016-07-20 | — | — | CN | claimed |
| CN-105452233-A | Piperidine and azepane derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICALS CO | 2016-03-30 | — | — | CN | claimed |
| EP-3562487-B1 | METALLOENZYME INHIBITOR COMPOUNDS | JI XING PHARMACEUTICALS HONG KONG LTD (HK) | 2023-11-29 | — | — | EP | disclosed |
| CN-111132974-B | Sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-110494431-B | Azacyclo derivative, preparation method and medical application thereof | 苏州浦合医药科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-20210322409-A1 | METALLOENZYME INHIBITOR COMPOUNDS | SELENITY THERAPEUTICS (BERMUDA), LTD. (BM) | 2021-10-21 | — | — | US | disclosed |
| CN-113301963-A | Substituted quinazolines as NLRP3 modulators for the treatment of cancer | 先天肿瘤免疫公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-113164481-A | Cycloalkane-1, 3-diamine derivatives | 第一三共株式会社 | 2021-07-23 | — | — | CN | disclosed |
| US-11040034-B2 | Metalloenzyme inhibitor compounds | PHASEBIO PHARMACEUTICALS, INC. (US) | 2021-06-22 | — | — | US | disclosed |
| CN-111132974-A | Novel sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-110494431-A | Nitrogen heterocycles derivative, preparation method and its medical usage | BEIJING YUEZHIKANGTAI BIOMEDICINES CO LTD | 2019-11-22 | — | — | CN | disclosed |
| US-20190008861-A1 | METALLOENZYME INHIBITOR COMPOUNDS | CORXEL PHARMACEUTICALS HONG KONG LIMITED (HK) | 2019-01-10 | — | — | US | disclosed |
| US-10085984-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS (BERMUDA), LTD. (BM) | 2018-10-02 | — | — | US | disclosed |
| US-20180185362-A1 | METALLOENZYME INHIBITOR COMPOUNDS | CORXEL PHARMACEUTICALS HONG KONG LIMITED (HK) | 2018-07-05 | — | — | US | disclosed |
| CN-105793249-A | Piperidine derivatives for the treatment or prevention of psychiatric and neurological disorders | 武田药品工业株式会社 | 2016-07-20 | — | — | CN | disclosed |
| CN-105452233-A | Piperidine and azepane derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICALS CO | 2016-03-30 | — | — | CN | disclosed |
| CN-104903320-A | Nitrogen-containing heterocylic compound or salt thereof | FUJIFILM CORP | 2015-09-09 | — | — | CN | disclosed |
| CN-101842359-A | Pyridazinone derivatives and use thereof as p2x7 receptor inhibitors | NISSAN CHEMICAL IND LTD | 2010-09-22 | — | — | CN | disclosed |
| CN-101495184-A | Aryl and heteroaryl substituted tetrahydrobenzazepine and its use to block reuptake of norepinephrine dopamine and serotonin | AMR TECHNOLOGY INC (US) | 2009-07-29 | — | — | CN | disclosed |