Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016478 | 1.00 | AKR1B1 (0.52) | AKR1B1TDP1TSHRHTTHPGD | |
| SCHEMBL9016481 | 1.00 | AKR1B1 (0.52) | AKR1B1TDP1TSHRHTTHPGD | |
| SCHEMBL8416291 | 0.80 | AKR1B1 (0.46) | AKR1B1TDP1ALDH1A1LMNABCAT2 | |
| SCHEMBL9016420 | 0.80 | AKR1B1 (0.46) | AKR1B1TDP1ALDH1A1LMNABCAT2 | |
| SCHEMBL8343067 | 0.80 | AKR1B1 (0.46) | AKR1B1TDP1ALDH1A1LMNABCAT2 | |
| SCHEMBL9016430 | 0.80 | USP2 (0.47) | TSHRHTTHPGDALDH1A1USP2 | |
| SCHEMBL2161081 | 0.79 | USP2 (0.47) | TSHRHTTHPGDALDH1A1USP2 | |
| SCHEMBL115054 | 0.79 | SRC (0.58) | AKR1B1TDP1LMNABCAT2SRC | |
| SCHEMBL10655491 | 0.79 | USP2 (0.47) | TSHRHTTHPGDALDH1A1USP2 | |
| SCHEMBL2161080 | 0.79 | USP2 (0.47) | TSHRHTTHPGDALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611230-B2 | 1,3,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease | PTC THERAPEUTICS, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| US-5962723-A | Method for producing benzyl bromide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0908446-A1 | Method for producing benzyl bromide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-04-14 | — | — | EP | disclosed |
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |