Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893812 | 0.81 | ALDH1A1 (0.44) | HPGDLMNAALDH1A1EGFRHTT | |
| SCHEMBL5283277 | 0.80 | KDM4E (0.43) | LMNAALDH1A1EGFRKDM4ETSHR | |
| SCHEMBL9011882 | 0.80 | ALDH1A1 (0.43) | HPGDLMNAALDH1A1EGFRHTT | |
| SCHEMBL9016478 | 0.80 | AKR1B1 (0.52) | USP2HPGDLMNAALDH1A1HTT | |
| SCHEMBL8338530 | 0.80 | AKR1B1 (0.52) | USP2HPGDLMNAALDH1A1HTT | |
| SCHEMBL9016481 | 0.80 | AKR1B1 (0.52) | USP2HPGDLMNAALDH1A1HTT | |
| SCHEMBL26075997 | 0.79 | KDM4E (0.43) | LMNAALDH1A1EGFRKDM4ETSHR | |
| SCHEMBL1554320 | 0.78 | KDM4E (0.53) | HPGDLMNAALDH1A1EGFRKDM4E | |
| SCHEMBL5026445 | 0.77 | KDM4E (0.42) | LMNAALDH1A1EGFRKDM4ETSHR | |
| SCHEMBL10655491 | 0.77 | USP2 (0.47) | USP2HPGDLMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |