Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410204 | 0.81 | CA2 (0.56) | CA1CA2CA9CA12CA4 | |
| SCHEMBL7369 | 0.81 | CA2 (0.56) | CA1CA2CA9CA12CA4 | |
| SCHEMBL9819451 | 0.79 | CA2 (0.41) | CA1CA2CA9CA12CA4 | |
| Methane SCHEMBL11237258 | 0.79 | CA2 (0.54) | CA1CA2CA9CA12CA4 | |
| Hydrochloric Acid SCHEMBL1807456 | 0.79 | CA2 (0.54) | CA1CA2CA9CA12CA4 | |
| Iodide SCHEMBL28558302 | 0.79 | CA2 (0.54) | CA1CA2CA9CA12CA4 | |
| Hydrochloric Acid SCHEMBL29377547 | 0.79 | CA2 (0.54) | CA1CA2CA9CA12CA4 | |
| SCHEMBL3638468 | 0.79 | CA2 (0.54) | CA1CA2CA9CA12CA4 | |
| Hydrogen Sulfide SCHEMBL27690672 | 0.79 | CA2 (0.54) | CA1CA2CA9CA12CA4 | |
| Water SCHEMBL27466610 | 0.79 | CA2 (0.54) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023193114-A1 | METHODS OF USING ATR INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2023-10-12 | — | — | WO | disclosed |
| WO-2021012049-A1 | SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2021-01-28 | — | — | WO | disclosed |
| US-5972844-A | Sulphonyl amino (thio) carbonyl-1,2,4-triazolin (thi) one derivatives and the use thereof as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5869681-A | PREPARING TRIAZOLINONE INTERMEDIATE BY HEATING HYDROCARBYLOXYCARBONYL-ISOSEMICARBAZIDE TO CYCLIZE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-09 | — | — | US | disclosed |
| US-5750718-A | CHEMICAL INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |
| US-5652372-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |
| US-5631380-A | CHEMICAL INTERMEDIATES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| US-5625074-A | Sulphonylaminocarbonyltriazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |
| US-5599944-A | Intermediates for herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| US-5597939-A | CHEMICAL INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-28 | — | — | US | disclosed |
| US-5405970-A | Unique chemical intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |
| US-5380863-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| US-5300480-A | Pre- and postemergent | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5276162-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| US-5241074-A | Hherbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| US-5149356-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |
| US-5094683-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| US-5057144-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |
| US-4743294-A | N'-(substituted-1,3,5-triazin-2-yl)-N\"-amino-N\"'-(substituted-benzenesulphonyl)-guanidines as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-10 | — | — | US | disclosed |
| US-4725305-A | PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-02-16 | — | — | US | disclosed |