Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070458 | 0.85 | KMT2A (0.47) | KMT2AALDH1A1HPGDEPHX1CA1 | |
| SCHEMBL6912270 | 0.78 | CA1 (0.63) | KMT2ACA1CA2CA9HTT | |
| SCHEMBL9309031 | 0.76 | KMT2A (0.61) | KMT2AALDH1A1HPGDCA1CA2 | |
| SCHEMBL7619550 | 0.72 | KMT2A (0.57) | KMT2AALDH1A1HPGDCA1CA2 | |
| SCHEMBL16394862 | 0.72 | KMT2A (0.52) | KMT2AALDH1A1CA1CA2CA9 | |
| SCHEMBL8913381 | 0.70 | CA1 (0.53) | KMT2AALDH1A1CA1CA2CA9 | |
| SCHEMBL2383968 | 0.70 | KMT2A (0.53) | KMT2AALDH1A1HPGDCA1CA2 | |
| SCHEMBL8746194 | 0.70 | KMT2A (0.53) | KMT2AALDH1A1HPGDCA1CA2 | |
| SCHEMBL2762566 | 0.70 | KMT2A (0.53) | KMT2AALDH1A1HPGDCA1CA2 | |
| SCHEMBL29482067 | 0.70 | KMT2A (0.53) | KMT2AALDH1A1HPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922727-A | 1-((SUBSTITUTED)CYCLOALK(EN)YLALKYL)-6-((SUB)PHENYL(CARBONYL, SULFIDE, OR OXO))-2,4-PYRIMIDINEDIONE DERIVATIVES HAVING SUPERIOR ANTIVIRAL ACTIVITIES; HIV | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 1999-07-13 | — | — | US | disclosed |