Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338624 | 0.93 | LRRK2 (0.49) | KIFC1ABCG2LRRK2 | |
| SCHEMBL4829673 | 0.90 | KIFC1 (0.60) | KIFC1ABCG2LRRK2POLBLMNA | |
| SCHEMBL4829669 | 0.90 | KIFC1 (0.60) | KIFC1ABCG2LRRK2POLBLMNA | |
| SCHEMBL4827862 | 0.89 | ABCG2 (0.59) | KIFC1ABCG2LRRK2SMPD1 | |
| SCHEMBL4827858 | 0.89 | ABCG2 (0.59) | KIFC1ABCG2LRRK2SMPD1 | |
| SCHEMBL8337501 | 0.87 | LRRK2 (0.47) | KIFC1ABCG2LRRK2SMPD1CTSB | |
| SCHEMBL8337386 | 0.87 | LRRK2 (0.49) | KIFC1ABCG2LRRK2POLBLMNA | |
| SCHEMBL4831380 | 0.86 | KIFC1 (0.64) | KIFC1ABCG2LRRK2POLBLMNA | |
| SCHEMBL4831384 | 0.86 | KIFC1 (0.64) | KIFC1ABCG2LRRK2POLBLMNA | |
| SCHEMBL4827793 | 0.85 | ABCG2 (0.62) | KIFC1ABCG2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |