Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843330 | 0.76 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5599990 | 0.71 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL5844233 | 0.70 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL5844172 | 0.68 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL5845315 | 0.66 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL5843406 | 0.66 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL5844486 | 0.65 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL5843364 | 0.64 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL5845722 | 0.64 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL21447165 | 0.64 | CRHR1 (0.56) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962479-A | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 1999-10-05 | — | — | US | disclosed |