Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.73 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401035 | 0.85 | TAAR1 (1.00) | TAAR1MAOBAOC3IDO1HTR2A | |
| SCHEMBL158935 | 0.85 | TAAR1 (1.00) | TAAR1MAOBAOC3IDO1HTR2A | |
| SCHEMBL6262320 | 0.84 | TAAR1 (0.64) | TAAR1MAOBAOC3IDO1LMNA | |
| Iodide SCHEMBL28728554 | 0.83 | TAAR1 (0.95) | TAAR1MAOBAOC3IDO1HTR2A | |
| Bromide SCHEMBL28598188 | 0.83 | TAAR1 (0.95) | TAAR1MAOBAOC3IDO1HTR2A | |
| Hydrochloric Acid SCHEMBL4080939 | 0.83 | TAAR1 (0.95) | TAAR1MAOBAOC3IDO1HTR2A | |
| SCHEMBL30261451 | 0.83 | TAAR1 (0.95) | TAAR1MAOBAOC3IDO1HTR2A | |
| SCHEMBL341815 | 0.81 | TAAR1 (0.58) | TAAR1HTR2A | |
| SCHEMBL307921 | 0.81 | — | — | |
| SCHEMBL32668885 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031506-A9 | PARALLEL SOLUTION PHASE SYNTHESIS OF LACTAMS | LILLY CO ELI (US) | 1999-09-16 | — | — | WO | disclosed |
| WO-1999031506-A1 | PARALLEL SOLUTION PHASE SYNTHESIS OF LACTAMS | ELI LILLY AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999002990-A1 | COMBINATORIAL PROCESS FOR PREPARING FUSED SUBSTITUTED PYRIMIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |