SCHEMBL341815

SCHEMBL341815

NCCc1ccccc1N

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 10/20 0.58
HTR2A P28223 3/20 0.52
HRH1 P35367 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
CYP2A6 P11509 2/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
CYP3A4 P08684 2/20 0.45
ALOX15 P16050 1/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
MPO P05164 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
NFKB1 P19838 1/20 0.42
HTR1D P28221 1/20 0.42
HTR1B P28222 1/20 0.42
HTR2C P28335 1/20 0.42
HTR7 P34969 1/20 0.42
CTSK P43235 1/20 0.42
HTR6 P50406 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25176434 0.97 TAAR1 (0.56) TAAR1HTR2AHRH1SMN1; SMN2CYP2A6
SCHEMBL234864 0.86 CYP3A4 (0.53) TAAR1SMN1; SMN2CYP3A4ALOX15CASP1
SCHEMBL5928190 0.85 SIGMAR1 (0.43) TAAR1HTR2ASMN1; SMN2CYP2A6LOXL2
SCHEMBL30498596 0.85 SIGMAR1 (0.43) TAAR1HTR2ASMN1; SMN2CYP2A6LOXL2
SCHEMBL2328308 0.83 MAOA (0.52) TAAR1HRH1SMN1; SMN2CYP3A4ALOX15
SCHEMBL224549 0.83 TAAR1 (0.70) TAAR1HTR2AHRH1SMN1; SMN2CYP2A6
SCHEMBL11871687 0.82 TAAR1 (0.44) TAAR1HTR2ASMN1; SMN2CYP3A4ALOX15
SCHEMBL23159894 0.81 ALOX15 (0.47) TAAR1HTR2ASMN1; SMN2CYP3A4ALOX15
SCHEMBL23159850 0.81 ALOX15 (0.47) TAAR1SMN1; SMN2CYP3A4ALOX15CASP1
SCHEMBL8339121 0.81 TAAR1 (0.73) TAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586481-A Method for preparing epoxy resin 浙江大学 2024-02-23 CN claimed
CN-117126573-B Anti-fouling wear-resistant nano fluorocarbon coating and preparation method thereof 江苏新福乐威涂料有限公司 2023-12-26 CN claimed
CN-117126573-A Anti-fouling wear-resistant nano fluorocarbon coating and preparation method thereof 江苏新福乐威涂料有限公司 2023-11-28 CN claimed
EP-2139936-B1 POLYURETHANE COMPOUND CONTAINING ASYMMETRIC DIALDIMINE SIKA TECH AG (CH) 2019-11-13 EP claimed
CN-104619788-B Super-normal structure black 卡博特公司 2018-04-03 CN claimed
US-9896583-B2 High structure carbon blacks CABOT CORPORATION 2018-02-20 US claimed
EP-2132245-B1 COMPOUND WITH LOW ISOCYANATE-MONOMER CONTENT CONTAINING ISOCYANATE AND ALDIMINO GROUPS SIKA TECH AG (CH) 2017-11-15 EP claimed
US-20160355686-A1 HIGH STRUCTURE CARBON BLACKS CABOT CORPORATION 2016-12-08 US claimed
US-9388300-B2 High structure carbon blacks CABOT CORPORATION (US) 2016-07-12 US claimed
US-9290608-B2 Asymmetric dialdimine-containing polyurethane composition SIKA TECHNOLOGY AG (CH) 2016-03-22 US claimed
US-20120142870-A1 Isocyanate- and Aldimine Group- Carrying Compounds with a Low Isocyanate Monomer Content SIKA TECHNOLOGY AG (CH) 2012-06-07 US claimed
US-20100021743-A1 ASYMMETRIC DIALDIMINE-CONTAINING POLYURETHANE COMPOSITION SIKA TECHNOLOGY AG (CH) 2010-01-28 US claimed
US-20100015450-A1 Isocyanate-and Aldimine Group-Carrying Compounds With a Low Isocyanate Monomer Content SIKA TECHNOLOGY AG (CH) 2010-01-21 US claimed
EP-2139936-A1 ASYMMETRIC DIALDIMINE-CONTAINING POLYURETHANE COMPOSITION Sika Technology AG (CH) 2010-01-06 EP claimed
EP-2132245-A1 ISOCYANATE- AND ALDIMINE GROUP-CARRYING COMPOUNDS WITH A LOW ISOCYANATE MONOMER CONTENT Sika Technology AG (CH) 2009-12-16 EP claimed
WO-2008116901-A1 ISOCYANATE- AND ALDIMINE GROUP-CARRYING COMPOUNDS WITH A LOW ISOCYANATE MONOMER CONTENT SIKA TECHNOLOGY AG (CH) 2008-10-02 WO claimed
WO-2008116902-A1 ASYMMETRIC DIALDIMINE-CONTAINING POLYURETHANE COMPOSITION SIKA TECHNOLOGY AG (CH) 2008-10-02 WO claimed
EP-1975186-A1 Compound with low isocyanate-monomer content containing isocyanate and aldimino groups Sika Technology AG (CH) 2008-10-01 EP claimed
EP-1975189-A1 Polyurethane compound containing asymmetric dialdimine Sika Technology AG (CH) 2008-10-01 EP claimed
EP-0474642-B1 CHELANTS NYCOMED SALUTAR INC (US) 1996-06-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142870-A1 Isocyanate- and Aldimine Group- Carrying Compounds with a Low Isocyanate Monomer Content IDH3A, ICAM1, VIM TAAR1 3349/4885HTR2A 3873/4885HRH1 758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.