Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.61 |
| ▸ | F2 | P00734 | 6/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581312 | 0.76 | F10 (1.00) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL7408094 | 0.76 | F10 (0.61) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL7404047 | 0.73 | F10 (0.61) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL7555146 | 0.73 | F10 (0.78) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL7552030 | 0.71 | F10 (0.63) | F10F2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7723352 | 0.69 | LMNA (0.51) | MRGPRX1ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL7721608 | 0.69 | MRGPRX1 (0.55) | MRGPRX1ALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL27837570 | 0.67 | LMNA (0.63) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL7549201 | 0.66 | F10 (0.55) | F10F2MRGPRX1CCR2ALDH1A1 | |
| SCHEMBL1457547 | 0.65 | F10 (0.57) | F10F2ST14PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883100-A | Benzamidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1999-03-16 | — | — | US | disclosed |