SCHEMBL8339351

SCHEMBL8339351

Cc1c(Cl)cc(F)cc1S(=O)(=O)Nc1ccc(C(F)(F)F)c(O[C@@H]2CCN(C)C2)c1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 19/20 0.66
P2RY4 P51582 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5835533 0.86 UTS2R (0.71) UTS2R
SCHEMBL5835543 0.86 UTS2R (0.71) UTS2R
SCHEMBL5835337 0.86 UTS2R (0.68) UTS2RP2RY4
SCHEMBL5835294 0.86 UTS2R (0.68) UTS2R
SCHEMBL5835346 0.86 UTS2R (0.68) UTS2RP2RY4
SCHEMBL8339645 0.86 UTS2R (0.68) UTS2R
SCHEMBL8342516 0.86 UTS2R (0.68) UTS2R
SCHEMBL5835287 0.86 UTS2R (0.68) UTS2R
SCHEMBL8338027 0.85 UTS2R (0.70) UTS2R
SCHEMBL5835628 0.85 UTS2R (0.69) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043366-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed