SCHEMBL8339382

SCHEMBL8339382

FC(Cl)=CCOc1cc(Cl)c(OCCCCOc2ccc(OC(F)(F)F)cc2)c(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.41
FFAR1 O14842 3/20 0.41
SCN5A Q14524 2/20 0.41
CYP2C9 P11712 1/20 0.41
MAOB P27338 1/20 0.40
AOC3 Q16853 1/20 0.40
PPARD Q03181 4/20 0.38
PPARA Q07869 4/20 0.38
CYP3A4 P08684 1/20 0.38
KCNH2 Q12809 1/20 0.38
CACNA1C Q13936 1/20 0.38
PPARG P37231 2/20 0.35
EPHX2 P34913 1/20 0.35
MRGPRX4 Q96LA9 1/20 0.34
ATM Q13315 1/20 0.34
SCN9A Q15858 1/20 0.33
CHRM5 P08912 1/20 0.33
SCN8A Q9UQD0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8339380 1.00 FFAR4 (0.41) FFAR4FFAR1SCN5ACYP2C9MAOB
SCHEMBL8339363 0.98 FFAR4 (0.41) FFAR4FFAR1SCN5ACYP2C9MAOB
SCHEMBL8339364 0.98 FFAR4 (0.41) FFAR4FFAR1SCN5ACYP2C9MAOB
SCHEMBL8519621 0.92 FFAR4 (0.44) FFAR4FFAR1SCN5ACYP2C9MAOB
SCHEMBL8338875 0.89 FFAR4 (0.40) FFAR4FFAR1SCN5ACYP2C9MAOB
SCHEMBL8338881 0.89 FFAR4 (0.40) FFAR4FFAR1SCN5ACYP2C9MAOB
SCHEMBL8406151 0.89 FFAR4 (0.44) FFAR4FFAR1SCN5ACYP2C9MAOB
SCHEMBL8409237 0.88 MAOB (0.40) FFAR4MAOBAOC3PPARDPPARA
SCHEMBL8409239 0.88 MAOB (0.40) FFAR4MAOBAOC3PPARDPPARA
SCHEMBL8413131 0.88 DRD4 (0.37) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787710-B1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1999-07-28 EP disclosed
US-5869506-A APPLYING TO ACARIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-09 US disclosed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP disclosed