Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.64 |
| ▸ | CTSL | P07711 | 15/20 | 0.61 |
| ▸ | CTSS | P25774 | 14/20 | 0.61 |
| ▸ | CTSB | P07858 | 6/20 | 0.61 |
| ▸ | CTSV | O60911 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103015 | 0.88 | CTSK (0.60) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6885960 | 0.86 | CTSK (0.59) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7098735 | 0.86 | CTSK (0.59) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL8337747 | 0.86 | CTSK (0.77) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6072824 | 0.86 | CTSK (0.77) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14131372 | 0.85 | CTSK (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14040700 | 0.85 | CTSK (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6740268 | 0.83 | CTSK (0.59) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6740265 | 0.83 | CTSK (0.59) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6073060 | 0.82 | CTSK (0.57) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |