Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413661 | 0.82 | HPGD (0.50) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL21694384 | 0.78 | MAPK9 (0.48) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL6240188 | 0.76 | LOXL2 (0.62) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL16383316 | 0.75 | HPGD (0.58) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL62420 | 0.75 | LOXL2 (0.66) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL29971249 | 0.75 | HPGD (0.58) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL10351068 | 0.75 | HPGD (0.58) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL2146969 | 0.75 | LOXL2 (0.66) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL30943481 | 0.74 | HPGD (0.57) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL1001902 | 0.74 | HPGD (0.57) | HPGDLOXL2HSD17B10CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008350-A | CATIONIC CYANINE DYES OF GIVEN FORMULA; USEFUL IN HEAT MODE RECORDING MATERIALS | AGFA-GEVAERT (BE) | 1999-12-28 | — | — | US | disclosed |
| EP-0719304-B1 | CYANINE DYES AND PROCESS FOR THE PRODUCTION | AGFA GEVAERT NV (BE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0719304-A1 | PROCESS FOR THE PRODUCTION OF CYANINE DYES | AGFA-GEVAERT N.V. (BE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007950-A1 | PROCESS FOR THE PRODUCTION OF CYANINE DYES | AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) | 1995-03-23 | — | — | WO | disclosed |