Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.52 |
| ▸ | RXRB | P28702 | 9/20 | 0.52 |
| ▸ | RXRG | P48443 | 7/20 | 0.52 |
| ▸ | RARB | P10826 | 5/20 | 0.52 |
| ▸ | RARG | P13631 | 4/20 | 0.52 |
| ▸ | RARA | P10276 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | CYP26B1 | Q9NR63 | 7/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21018213 | 0.82 | RXRA (0.60) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8331809 | 0.82 | RXRA (0.60) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL21017021 | 0.82 | RXRA (0.60) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8332402 | 0.82 | RXRA (0.60) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8332983 | 0.80 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL21017967 | 0.80 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8332791 | 0.80 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8606352 | 0.80 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL22106180 | 0.77 | RXRA (0.55) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL22076595 | 0.77 | RXRA (0.55) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999008992-A1 | 2,4-PENTADIENOIC ACID DERIVATIVES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN SALES, INC. (US) | 1999-02-25 | — | — | WO | disclosed |