SCHEMBL8340557

SCHEMBL8340557

CN1C(=O)CC(=O)C=C1N

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7945735 0.65
SCHEMBL23894741 0.65 GSK3A (0.38)
SCHEMBL145601 0.61 KMT2A (0.35)
SCHEMBL23153195 0.61 GSK3A (0.35)
SCHEMBL5503560 0.59
SCHEMBL31439229 0.59 KMT2A (0.33)
SCHEMBL4420912 0.57 BRPF1 (0.53)
SCHEMBL35261 0.57
SCHEMBL6518017 0.57 BRPF1 (0.53)
SCHEMBL13239543 0.57 CYP1A2 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004014384-A2 CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2004-02-19 WO disclosed