Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198618 | 0.77 | FOLH1 (0.50) | HTTMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL28007312 | 0.76 | HTT (0.56) | HTTMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL9958482 | 0.75 | HTT (0.41) | HTTMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL27203725 | 0.75 | MEN1 (0.47) | HTTMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL3900444 | 0.75 | HTT (0.58) | HTTMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL16431353 | 0.74 | F7 (0.51) | HTTF7F3 | |
| SCHEMBL3748239 | 0.73 | PTPN1 (0.52) | HTTMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL8346381 | 0.72 | HTT (0.58) | HTTMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL29594226 | 0.72 | HTT (0.46) | HTTMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL13105380 | 0.71 | FOLH1 (0.56) | HTTCYP2D6CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001880-A | DISUBSTITUTED N-(2-DIALKYLAMINOETHYL)BENZAMIDE DERIVATIVES OF GIVEN FORMULA; ANTIBACTERIAL ACTIVITY AGAINST HELICOBACTER PYROLI, ADMINISTERING FOR THE PREVENTION OR CURE OF PEPTIC ULCERS | SHISEIDO CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |