Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15940242 | 0.87 | CTSK (0.55) | PTPN1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL15940239 | 0.87 | CTSK (0.55) | PTPN1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1908071 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2AHPGDALDH1A1CA12 | |
| SCHEMBL10828138 | 0.80 | ALDH1A1 (0.47) | PTPN1HTTMEN1KMT2AHPGD | |
| SCHEMBL28007312 | 0.79 | HTT (0.56) | PTPN1HTTMEN1KMT2AHPGD | |
| SCHEMBL17912502 | 0.79 | CA12 (0.46) | PTPN1HTTMEN1KMT2AHPGD | |
| SCHEMBL39010 | 0.78 | CA12 (0.57) | PTPN1HTTMEN1KMT2AHPGD | |
| SCHEMBL28126806 | 0.78 | CA12 (0.57) | PTPN1HTTMEN1KMT2AHPGD | |
| SCHEMBL27203725 | 0.78 | MEN1 (0.47) | PTPN1HTTMEN1KMT2AHPGD | |
| SCHEMBL7198618 | 0.77 | FOLH1 (0.50) | HTTMEN1KMT2AHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101903513-A | Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms | UNIV COLORADO | 2010-12-01 | — | — | CN | claimed |
| US-20060035981-A1 | Inhibition of anaerobic glucose metabolism and corresponding composition as a natural non-toxic approach to cancer treatment | MAZZIO ELIZABETH A | 2006-02-16 | — | — | US | claimed |
| WO-2006017494-A2 | INHIBITION OF ANAEROBIC GLUCOSE METABOLISM | MAZZIO ELIZABETH (US) | 2006-02-16 | — | — | WO | claimed |
| US-8802161-B2 | Herbal composition and method of use for the treatment of cancer | FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (US) | 2014-08-12 | — | — | US | disclosed |
| CN-101218352-B | Production of carotenoids in oleaginous yeast and fungi | MICROBIA INC | 2013-09-04 | — | — | CN | disclosed |
| CN-101903513-B | Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms | UNIV COLORADO | 2013-08-21 | — | — | CN | disclosed |
| CN-101903513-A | Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms | UNIV COLORADO | 2010-12-01 | — | — | CN | disclosed |
| US-20100209388-A1 | Nutraceutical composition and method of use for treatment / prevention of cancer | FLORIDA A & M UNIVERSITY | 2010-08-19 | — | — | US | disclosed |
| CN-101218352-A | Production of carotenoids in oleaginous yeast and fungi | MICROBIA INC (US) | 2008-07-09 | — | — | CN | disclosed |
| US-20070248693-A1 | Nutraceutical composition and method of use for treatment / prevention of cancer | MAZZIO ELIZABETH | 2007-10-25 | — | — | US | disclosed |
| US-20060068386-A1 | Complete genome and protein sequence of the hyperthermophile methanopyrus kandleri av19 and monophyly of archael methanogens and methods of use thereof | SLESAREV ALEXEI | 2006-03-30 | — | — | US | disclosed |
| US-20060035981-A1 | Inhibition of anaerobic glucose metabolism and corresponding composition as a natural non-toxic approach to cancer treatment | MAZZIO ELIZABETH A | 2006-02-16 | — | — | US | disclosed |
| WO-2006017494-A2 | INHIBITION OF ANAEROBIC GLUCOSE METABOLISM | MAZZIO ELIZABETH (US) | 2006-02-16 | — | — | WO | disclosed |
| US-4169940-A | CHEMICAL OXIDATION OF NOVOBIOCIN AND PRODUCTS OBTAINED THEREFROM | THE UPJOHN COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4147704-A | Derivatives of novobiocin | THE UPJOHN COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209388-A1 | Nutraceutical composition and method of use for treatment / prevention of cancer | DLD, MDH1, MDH2 | PTPN1 4860/4885HTT 4223/4885MEN1 624/4885 |
| US-20060035981-A1 | Inhibition of anaerobic glucose metabolism and corresponding composition as a natural non-toxic approach to cancer treatment | G6PD, PDK2, SDHA | PTPN1 1577/4885HTT 4848/4885MEN1 2991/4885 |
| US-20070248693-A1 | Nutraceutical composition and method of use for treatment / prevention of cancer | DLD, DERA, ALDOA | PTPN1 4648/4885HTT 4472/4885MEN1 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.