Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL8338831 | 0.89 | GRIK1 (0.54) | SLC7A5SLC1A2SLC1A3GRIK1GRIK2 | |
| Leucine SCHEMBL8340630 | 0.89 | GRIK1 (0.54) | SLC7A5SLC1A2SLC1A3GRIK1GRIK2 | |
| SCHEMBL1116199 | 0.87 | FOLH1 (0.51) | GSRFOLH1CPB2SLC6A5 | |
| SCHEMBL29741342 | 0.87 | FOLH1 (0.51) | GSRFOLH1CPB2SLC6A5 | |
| SCHEMBL787393 | 0.87 | FOLH1 (0.51) | GSRFOLH1CPB2SLC6A5 | |
| SCHEMBL5869685 | 0.82 | FOLH1 (0.45) | GSRFOLH1CPB2SLC6A5 | |
| SCHEMBL8254457 | 0.82 | FOLH1 (0.45) | GSRFOLH1CPB2SLC6A5 | |
| Lysine SCHEMBL1258691 | 0.80 | GSR (0.74) | SLC7A5GSRSLC1A2SLC1A3GRIK1 | |
| Lysine SCHEMBL27839054 | 0.80 | GSR (0.74) | SLC7A5GSRSLC1A2SLC1A3GRIK1 | |
| Lysine SCHEMBL27807246 | 0.80 | GSR (0.74) | SLC7A5GSRSLC1A2SLC1A3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |