SCHEMBL5869685

SCHEMBL5869685

CC(NC(CCCN)C(=O)O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.45
GABRR1 P24046 2/20 0.42
CPB2 Q96IY4 7/20 0.41
GSR P00390 1/20 0.39
SLC6A5 Q9Y345 1/20 0.38
RNPEP Q9H4A4 1/20 0.38
ACE P12821 2/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
GGT1 P19440 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8254457 1.00 FOLH1 (0.45) FOLH1GABRR1CPB2GSRSLC6A5
SCHEMBL29741342 0.94 FOLH1 (0.51) FOLH1GABRR1CPB2GSRSLC6A5
SCHEMBL787393 0.94 FOLH1 (0.51) FOLH1GABRR1CPB2GSRSLC6A5
SCHEMBL1116199 0.94 FOLH1 (0.51) FOLH1GABRR1CPB2GSRSLC6A5
SCHEMBL7027611 0.86 FOLH1 (0.46) FOLH1GABRR1CPB2GSRSLC6A5
SCHEMBL7027613 0.86 FOLH1 (0.46) FOLH1GABRR1CPB2GSRSLC6A5
SCHEMBL3725106 0.86 FOLH1 (0.46) FOLH1GABRR1CPB2GSRSLC6A5
SCHEMBL4783069 0.85 FOLH1 (0.45) FOLH1GABRR1CPB2GSRSLC6A5
SCHEMBL4783065 0.85 FOLH1 (0.45) FOLH1GABRR1CPB2GSRSLC6A5
SCHEMBL9810181 0.83 ACE (0.43) FOLH1CPB2ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9434924-B2 Cell culture method and cell culture kit NIPRO CORPORATION (JP) 2016-09-06 US claimed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-11060079-B2 Methods and microorganisms for producing flavors and fragrance chemicals ARDRA INC. (CA) 2021-07-13 US disclosed
US-20190177713-A1 METHODS AND MICROORGANISMS FOR PRODUCING FLAVORS AND FRAGRANCE CHEMICALS ARDRA INC. (CA) 2019-06-13 US disclosed
EP-2700707-B1 CELL CULTURE METHOD AND CELL CULTURE KIT NIPRO CORP (JP) 2018-06-06 EP disclosed
US-20140087465-A1 CELL CULTURE METHOD AND CELL CULTURE KIT NIPRO CORPORATION (JP) 2014-03-27 US disclosed
EP-2700707-A1 CELL CULTURE METHOD AND CELL CULTURE KIT Nipro Corporation (JP) 2014-02-26 EP disclosed
US-7045532-B2 ACE-2 modulating compounds and methods of use thereof MILLENNIUM PHARMACEUTICALS, INC. (US) 2006-05-16 US disclosed
US-6632830-B1 Blood pressure related disease or disorder, cell proliferation disorder, kidney disorder, kinetensin associated disorder, inflammation associated disorder, or an allergic disorder MILLENNIUM PHARMACEUTICALS, INC. 2003-10-14 US disclosed