Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056990 | 0.79 | — | — | |
| SCHEMBL16336286 | 0.79 | — | — | |
| SCHEMBL2428834 | 0.79 | — | — | |
| SCHEMBL9303709 | 0.79 | — | — | |
| SCHEMBL2621359 | 0.79 | — | — | |
| SCHEMBL278517 | 0.79 | — | — | |
| SCHEMBL1154321 | 0.77 | — | — | |
| SCHEMBL9517234 | 0.77 | — | — | |
| SCHEMBL13948925 | 0.77 | — | — | |
| SCHEMBL17946858 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012572-A1 | COMPOUNDS AND METHOD FOR THE PREVENTION AND TREATMENT OF DIABETIC RETINOPATHY | UNIVERSITY OF FLORIDA (US) | 1999-03-18 | — | — | WO | disclosed |