Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5845283 | 0.79 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL8341883 | 0.79 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL5599990 | 0.73 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL16606728 | 0.73 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL5845672 | 0.72 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL5844100 | 0.70 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL5843759 | 0.70 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL5845956 | 0.70 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL8139037 | 0.69 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL21447163 | 0.69 | CRHR1 (0.48) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962479-A | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 1999-10-05 | — | — | US | disclosed |