SCHEMBL8341899

SCHEMBL8341899

OC(CCl)CNCC(O)CCl

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 1/20 0.45
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18513165 0.84 CA1 (0.35) CA1CA2CA9TSHR
SCHEMBL11508923 0.83
SCHEMBL11795818 0.83 PKM (0.39) CA1CA2CA9ALDH1A1TSHR
SCHEMBL30819055 0.81
SCHEMBL17832294 0.79 PKM (0.37) CA1CA2CA9ALDH1A1KDM4E
SCHEMBL28379728 0.79
SCHEMBL14161191 0.78
SCHEMBL17223962 0.77 PKM (0.35) CA1CA2CA9
SCHEMBL6443493 0.77
Hydrochloric Acid SCHEMBL27738305 0.77 CA1 (0.33) CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207408-B With N, the manufacturing method of the compound of bis- (2- hydroxyl -3- chloropropyl) amino of N- 东丽精细化工株式会社 2019-06-07 CN claimed
WO-1999002465-A1 SET-ACCELERATING MIXTURE FOR CONCRETE NYFOTEK AS (NO) 1999-01-21 WO claimed
EP-3257840-B1 METHOD FOR PRODUCING COMPOUND HAVING N,N-BIS(2-HYDROXY-3-CHLOROPROPYL)AMINO GROUP TORAY FINECHEMICALS CO LTD (JP) 2019-07-10 EP disclosed
CN-107207408-B With N, the manufacturing method of the compound of bis- (2- hydroxyl -3- chloropropyl) amino of N- 东丽精细化工株式会社 2019-06-07 CN disclosed
CN-107207408-B With N, the manufacturing method of the compound of bis- (2- hydroxyl -3- chloropropyl) amino of N- 东丽精细化工株式会社 2019-06-07 CN disclosed
CN-107207408-B With N, the manufacturing method of the compound of bis- (2- hydroxyl -3- chloropropyl) amino of N- 东丽精细化工株式会社 2019-06-07 CN disclosed
US-10017485-B2 Manufacturing method for compound having N,N-bis(2-hydroxy-3-chloropropyl)amino group TORAY FINE CHEMICALS CO., LTD. (JP) 2018-07-10 US disclosed
US-20180030013-A1 MANUFACTURING METHOD FOR COMPOUND HAVING N,N-BIS(2-HYROXY-3-CHLOROPROPYL)AMINO GROUP TORAY FINE CHEMICALS CO., LTD. (JP) 2018-02-01 US disclosed
EP-3257840-A1 METHOD FOR PRODUCING COMPOUND HAVING N,N-BIS(2-HYDROXY-3-CHLOROPROPYL)AMINO GROUP Toray Fine Chemicals Co., Ltd. (JP) 2017-12-20 EP disclosed
WO-1999002465-A1 SET-ACCELERATING MIXTURE FOR CONCRETE NYFOTEK AS (NO) 1999-01-21 WO disclosed
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
US-4054542-A Amine-epichlorohydrin polymeric compositions BUCKMAN LABORATORIES, INC. (US) 1977-10-18 US disclosed