Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341966 | 1.00 | HIF1A (0.46) | HIF1AAAK1SGMS2MAPK1POLB | |
| SCHEMBL7685375 | 0.86 | HIF1A (0.52) | HIF1AOPRL1LMNA | |
| SCHEMBL7685378 | 0.86 | HIF1A (0.52) | HIF1AOPRL1LMNA | |
| SCHEMBL8342162 | 0.86 | HIF1A (0.46) | HIF1ASGMS2OPRL1MEN1KMT2A | |
| SCHEMBL8342165 | 0.86 | HIF1A (0.46) | HIF1ASGMS2OPRL1MEN1KMT2A | |
| SCHEMBL8338517 | 0.83 | HIF1A (0.42) | HIF1ASGMS2POLBNPSR1NPC1 | |
| SCHEMBL8338515 | 0.83 | HIF1A (0.42) | HIF1ASGMS2POLBNPSR1NPC1 | |
| SCHEMBL8336087 | 0.83 | HIF1A (0.44) | HIF1AAAK1SGMS2MAPT | |
| SCHEMBL8336079 | 0.83 | HIF1A (0.44) | HIF1AAAK1SGMS2MAPT | |
| SCHEMBL829037 | 0.81 | HIF1A (0.49) | HIF1ASGMS2POLBTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968875-A | FUNGICIDES FOR PLANTS | DOW AGROSCIENCES LLC (US) | 1999-10-19 | — | — | US | disclosed |