Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342165 | 1.00 | HIF1A (0.46) | HIF1AGABRA5PDCD1CD274ULK1 | |
| SCHEMBL8341966 | 0.86 | HIF1A (0.46) | HIF1ASGMS2MEN1KMT2AOPRL1 | |
| SCHEMBL8341964 | 0.86 | HIF1A (0.46) | HIF1ASGMS2MEN1KMT2AOPRL1 | |
| SCHEMBL8339227 | 0.85 | HIF1A (0.43) | HIF1AALDH1A1SGMS2 | |
| SCHEMBL8339226 | 0.85 | HIF1A (0.43) | HIF1AALDH1A1SGMS2 | |
| SCHEMBL829036 | 0.81 | HIF1A (0.49) | HIF1ASGMS2 | |
| SCHEMBL829037 | 0.81 | HIF1A (0.49) | HIF1ASGMS2 | |
| SCHEMBL7685375 | 0.80 | HIF1A (0.52) | HIF1AULK1OPRL1 | |
| SCHEMBL7685378 | 0.80 | HIF1A (0.52) | HIF1AULK1OPRL1 | |
| SCHEMBL8399045 | 0.80 | HIF1A (0.57) | HIF1AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968875-A | FUNGICIDES FOR PLANTS | DOW AGROSCIENCES LLC (US) | 1999-10-19 | — | — | US | disclosed |