Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.43 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156930 | 0.78 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL6156937 | 0.70 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30352570 | 0.69 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7913450 | 0.69 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7916072 | 0.68 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL7916056 | 0.68 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL22713924 | 0.66 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7617504 | 0.66 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3132672 | 0.66 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4269812 | 0.65 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4DPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869515-A | TREATING ASTHMATIC OR ATOPIC DISEASES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-02-09 | — | — | US | disclosed |