SCHEMBL8342801

SCHEMBL8342801

CC(O)c1sc(S(=O)(=O)Nc2ccc(C(F)(F)F)c(O[C@@H]3CCN(C)C3)c2)cc1Br

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6819959 0.89 UTS2R (0.70) UTS2R
SCHEMBL5745067 0.89 UTS2R (0.70) UTS2R
SCHEMBL8342188 0.87 UTS2R (0.60) UTS2R
SCHEMBL5743168 0.87 UTS2R (0.67) UTS2R
SCHEMBL6819512 0.87 UTS2R (0.67) UTS2R
SCHEMBL6823259 0.84 UTS2R (0.63) UTS2R
SCHEMBL6822827 0.84 UTS2R (0.67) UTS2R
SCHEMBL6822825 0.84 UTS2R (0.67) UTS2R
SCHEMBL6828353 0.82 UTS2R (0.63) UTS2R
SCHEMBL6828351 0.82 UTS2R (0.63) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043366-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed