Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.60 |
| ▸ | GSK3A | P49840 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071672 | 0.86 | GSK3B (0.76) | GSK3BGSK3A | |
| SCHEMBL6071679 | 0.86 | GSK3B (0.76) | GSK3BGSK3A | |
| SCHEMBL6363127 | 0.86 | ALDH1A1 (0.61) | GSK3BGSK3AKDM4EALDH1A1RAB9A | |
| SCHEMBL6363130 | 0.86 | ALDH1A1 (0.61) | GSK3BGSK3AKDM4EALDH1A1RAB9A | |
| SCHEMBL6071715 | 0.77 | GSK3B (0.61) | GSK3BGSK3A | |
| SCHEMBL6071712 | 0.77 | GSK3B (0.61) | GSK3BGSK3A | |
| SCHEMBL8344625 | 0.76 | GSK3B (1.00) | GSK3BGSK3A | |
| SCHEMBL6071408 | 0.76 | GSK3B (0.76) | GSK3BGSK3A | |
| SCHEMBL6071428 | 0.76 | GSK3B (0.76) | GSK3BGSK3A | |
| SCHEMBL6071677 | 0.76 | GSK3B (0.75) | GSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009597-A2 | PYRAZOLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |