Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945424 | 0.87 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2PTPN1LMNANPSR1 | |
| SCHEMBL4421983 | 0.87 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2PTPN1LMNANPSR1 | |
| SCHEMBL4945427 | 0.87 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2PTPN1LMNANPSR1 | |
| SCHEMBL4421987 | 0.87 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2PTPN1LMNANPSR1 | |
| SCHEMBL5743539 | 0.87 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2PTPN1LMNANPSR1 | |
| SCHEMBL4416015 | 0.87 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2PTPN1LMNANPSR1 | |
| SCHEMBL5946005 | 0.87 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2PTPN1LMNANPSR1 | |
| SCHEMBL13709421 | 0.85 | PTPN1 (0.49) | HSD17B10SMN1; SMN2PTPN1HDAC8LMNA | |
| SCHEMBL4941942 | 0.85 | MMP1 (0.40) | HSD17B10SMN1; SMN2PTPN1HDAC8LMNA | |
| SCHEMBL4941935 | 0.85 | MMP1 (0.40) | HSD17B10SMN1; SMN2PTPN1HDAC8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005249-A1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-01-15 | — | — | WO | disclosed |