Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 12/20 | 0.61 |
| ▸ | DRD2 | P14416 | 10/20 | 0.61 |
| ▸ | HTR1D | P28221 | 3/20 | 0.58 |
| ▸ | HTR1B | P28222 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343194 | 1.00 | DRD3 (0.61) | DRD3DRD2HTR1DHTR1BHTR1A | |
| SCHEMBL7290158 | 1.00 | DRD3 (0.61) | DRD3DRD2HTR1DHTR1BHTR1A | |
| SCHEMBL1726523 | 0.91 | DRD2 (0.50) | DRD3DRD2HTR1DHTR1BHTR1A | |
| SCHEMBL7298755 | 0.83 | DRD2 (0.65) | DRD3DRD2HTR1DHTR1BHTR1A | |
| SCHEMBL8339894 | 0.83 | DRD2 (0.65) | DRD3DRD2HTR1DHTR1BHTR1A | |
| SCHEMBL8339900 | 0.83 | DRD2 (0.65) | DRD3DRD2HTR1DHTR1BHTR1A | |
| SCHEMBL8694462 | 0.78 | DRD3 (0.58) | DRD3DRD2HTR1ADRD4 | |
| SCHEMBL9752126 | 0.76 | DRD3 (0.61) | DRD3DRD2HTR1DHTR1BHTR1A | |
| SCHEMBL7292160 | 0.76 | DRD2 (0.59) | DRD3DRD2HTR1DHTR1BHTR1A | |
| SCHEMBL8313410 | 0.74 | HTR1D (1.00) | HTR1DHTR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945566-A | Amino compounds of 6,7,8,9-tetrahydro-cyclopenta a!naphthalene and of 2,3-dihydro-cyclopenta e!indene | ADIR ET COMPAGNIE (FR) | 1999-08-31 | — | — | US | disclosed |