Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643941 | 0.85 | MMP3 (0.59) | MMP3MMP2MMP1FKBP1A | |
| SCHEMBL7643934 | 0.84 | MMP3 (0.48) | MMP3MMP2MMP1CPA1CPA2 | |
| SCHEMBL7401524 | 0.78 | MMP3 (0.66) | MMP3MMP2MMP1FKBP1A | |
| SCHEMBL7401520 | 0.78 | MMP3 (0.54) | MMP3MMP2MMP1FKBP1ACPA1 | |
| SCHEMBL7402167 | 0.77 | MMP3 (0.59) | MMP3MMP2MMP1FKBP1A | |
| SCHEMBL7402164 | 0.76 | MMP3 (0.51) | MMP3MMP2MMP1FKBP1ACPA1 | |
| SCHEMBL8858202 | 0.74 | MMP3 (0.54) | MMP3MMP2MMP1FKBP1ACPA1 | |
| SCHEMBL8344554 | 0.73 | HPGD (0.38) | MMP3MMP1 | |
| SCHEMBL8343741 | 0.70 | MMP3 (0.47) | MMP3MMP2MMP1FKBP1ACPA1 | |
| SCHEMBL7391702 | 0.69 | MMP3 (0.64) | MMP3MMP2MMP1FKBP1ACPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |