Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345333 | 0.89 | TSHR (0.64) | TSHRMAPTRAB9AL3MBTL1CASP3 | |
| Terephthalic Acid SCHEMBL18394717 | 0.83 | TSHR (0.70) | TSHRMAPTRAB9AL3MBTL1CASP3 | |
| Terephthalic Acid SCHEMBL8811649 | 0.83 | TSHR (0.70) | TSHRMAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL27555709 | 0.83 | TSHR (0.70) | TSHRMAPTRAB9AL3MBTL1CASP3 | |
| Terephthalic Acid SCHEMBL4349174 | 0.83 | TSHR (0.70) | TSHRMAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL63466 | 0.83 | TSHR (0.70) | TSHRMAPTRAB9AL3MBTL1CASP3 | |
| Terephthalic Acid SCHEMBL27517516 | 0.82 | TSHR (0.63) | TSHRMAPTRAB9AL3MBTL1CASP3 | |
| Terephthalic Acid SCHEMBL27796382 | 0.82 | TSHR (0.63) | TSHRMAPTRAB9AL3MBTL1CASP3 | |
| SCHEMBL2395112 | 0.81 | TSHR (0.67) | TSHRMAPTRAB9AL3MBTL1CASP3 | |
| Hydrochloric Acid SCHEMBL296016 | 0.81 | TSHR (0.67) | TSHRMAPTRAB9AL3MBTL1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36477-E | 4-(3,5-BIS(TRIMETHYLSILYLPHENYL)CARBOXAMIDO)BENZOIC ACID; DIFFERENTIATION-INDUCING REAGENT OR CELLS; ANTICARCINOGENTIC, -TUMOR,-INFLAMMATORY AND -PROLIFERATIVE AGENTS; PSORIASIS; LEUKEMIA; IMMUNOLOGY | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0337176-B1 | Novel benzoic acid derivatives and process for preparing the same | SHUDO KOICHI (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5155249-A | Differentiating neoplastic cells, treating psoriasis, immune or inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| US-5081271-A | Differentiation-inducing agent for neoplastic cells; therapeutic agent for psoriasis or immune and inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0337176-A2 | Novel benzoic acid derivatives and process for preparing the same | Shudo, Koichi, Prof. Dr. (JP) | 1989-10-18 | — | — | EP | disclosed |