Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292143 | 0.83 | ALDH1A1 (0.34) | MAOBGRM4SCDCNR1CNR2 | |
| SCHEMBL6289383 | 0.77 | MAOB (0.35) | MAOBGRM4SCDALDH1A1S1PR1 | |
| SCHEMBL6292698 | 0.74 | ALDH1A1 (0.35) | CNR1CNR2ALDH1A1HSD17B10GAA | |
| SCHEMBL6289353 | 0.73 | DAO (0.34) | CNR1CNR2ALDH1A1HSD17B10GAA | |
| SCHEMBL6289343 | 0.73 | ALDH1A1 (0.34) | CNR1CNR2ALDH1A1HSD17B10GAA | |
| SCHEMBL6680077 | 0.71 | NR1H2 (0.40) | MAOBALDH1A1KDM4CHDAC6 | |
| SCHEMBL6288960 | 0.71 | ALDH1A1 (0.38) | CNR1CNR2ALDH1A1HSD17B10GAA | |
| SCHEMBL6292748 | 0.71 | MAOB (0.43) | MAOBSCDALDH1A1S1PR3MAPT | |
| SCHEMBL6289019 | 0.70 | ALDH1A1 (0.35) | CNR1CNR2ALDH1A1HSD17B10GAA | |
| SCHEMBL6288793 | 0.67 | ALDH1A1 (0.33) | GRM4ALDH1A1HSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014384-A2 | CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |