Methane

Methane

SCHEMBL8344178

C.CCCCCOS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.46
RECQL P46063 2/20 0.46
TSHR P16473 2/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.46
EPHX2 P34913 1/20 0.46
BLM P54132 1/20 0.46
CA1 P00915 11/20 0.44
CA2 P00918 11/20 0.44
CA9 Q16790 10/20 0.44
CA12 O43570 5/20 0.43
CA7 P43166 4/20 0.43
CA14 Q9ULX7 3/20 0.43
CA3 P07451 2/20 0.43
CA4 P22748 2/20 0.43
CA6 P23280 2/20 0.43
CA5A P35218 2/20 0.43
CA5B Q9Y2D0 2/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283871 0.98 MCHR1 (0.47) MCHR1RECQLTSHRGLAHPGD
SCHEMBL5015857 0.97 RECQL (0.50) MCHR1RECQLTSHRGLAHPGD
SCHEMBL3088278 0.97 RECQL (0.50) MCHR1RECQLTSHRGLAHPGD
SCHEMBL812482 0.97 RECQL (0.50) MCHR1RECQLTSHRGLAHPGD
SCHEMBL974536 0.97 RECQL (0.50) MCHR1RECQLTSHRGLAHPGD
SCHEMBL8085071 0.97 RECQL (0.50) MCHR1RECQLTSHRGLAHPGD
SCHEMBL4193998 0.97 RECQL (0.50) MCHR1RECQLTSHRGLAHPGD
SCHEMBL10725263 0.97 RECQL (0.50) MCHR1RECQLTSHRGLAHPGD
SCHEMBL2194649 0.97 RECQL (0.50) MCHR1RECQLTSHRGLAHPGD
SCHEMBL345885 0.97 RECQL (0.50) MCHR1RECQLTSHRGLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922239-A AN INEXPENSIVE BASE OIL USE AS A WORKING FLUID COMPOSITION FOR A REFRIGERATING MACHINE, HAVING EXCELLENT COMPATIBILITY WITH HYDROFLUOROCARBONS, HYDROLYSIS RESISTANCE, ADEQUATE KINEMATIC VISCOSITY, GOOD FLUIDITY AT LOW TEMPERATURES KAO CORPORATION (JP) 1999-07-13 US disclosed
US-5869702-A SPECIALTY OILS FOR REFRIGERATORS KAO CORPORATION (JP) 1999-02-09 US disclosed
US-5720895-A CONSISTS OF HYDROFLUOROCARBONS, A REFRIGERATION OIL CONTAINING POLYOL ETHER DERIVATIVES AS A BASE OIL KAO CORPORATION (JP) 1998-02-24 US disclosed
EP-0696564-A1 Polyol ether derivatives and production methods therefor KAO CORPORATION (JP) 1996-02-14 EP disclosed