Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 11/20 | 0.46 |
| ▸ | CA2 | P00918 | 11/20 | 0.46 |
| ▸ | CA9 | Q16790 | 10/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA7 | P43166 | 4/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345885 | 0.98 | RECQL (0.50) | MCHR1RECQLTSHRGLAHPGD | |
| SCHEMBL5015857 | 0.98 | RECQL (0.50) | MCHR1RECQLTSHRGLAHPGD | |
| SCHEMBL3088278 | 0.98 | RECQL (0.50) | MCHR1RECQLTSHRGLAHPGD | |
| SCHEMBL974536 | 0.98 | RECQL (0.50) | MCHR1RECQLTSHRGLAHPGD | |
| SCHEMBL8085071 | 0.98 | RECQL (0.50) | MCHR1RECQLTSHRGLAHPGD | |
| Methane SCHEMBL8344178 | 0.98 | MCHR1 (0.46) | MCHR1RECQLTSHRGLAHPGD | |
| SCHEMBL4193998 | 0.98 | RECQL (0.50) | MCHR1RECQLTSHRGLAHPGD | |
| SCHEMBL10725263 | 0.98 | RECQL (0.50) | MCHR1RECQLTSHRGLAHPGD | |
| SCHEMBL2194649 | 0.98 | RECQL (0.50) | MCHR1RECQLTSHRGLAHPGD | |
| SCHEMBL2134205 | 0.98 | RECQL (0.50) | MCHR1RECQLTSHRGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 819 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172667-A2 | SUBSTITUTED IMIDAZO[1,5-a]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-09-14 | — | — | WO | claimed |
| CN-112980421-B | Acidic degradable fracturing ball and preparation method thereof | 北京易联结科技发展有限公司 | 2022-06-21 | — | — | CN | claimed |
| US-20220056054-A1 | METHODS OF PREPARATION OF AMINOBORANES AND APPLICATIONS FOR BORYLATION AND SUZUKI COUPLING | PURDUE RESEARCH FOUNDATION (US) | 2022-02-24 | — | — | US | claimed |
| CN-112980421-A | Acidic degradable fracturing ball and preparation method thereof | 北京易联结科技发展有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-110357889-A | Protein degradation target compound, its antitumor application thereof, wherein mesosome and intermediate application | 上海科技大学 | 2019-10-22 | — | — | CN | claimed |
| US-20160229778-A1 | DIRECT B-ARYLATION OF CARBONYL COMPOUNDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2016-08-11 | — | — | US | claimed |
| CN-104292467-A | New amino acid-modified siloxanes, process for preparing them and application | EVONIK INDUSTRIES AG | 2015-01-21 | — | — | CN | claimed |
| CN-103201329-B | Composition made of polymers and electrically conductive carbon | EVONIK GOLDSCHMIDT GMBH | 2014-09-03 | — | — | CN | claimed |
| CN-103333439-A | Transparent permanent antistatic transparent polyvinylidene fluoride composition and preparation method thereof | SHANGYU JAVA MACROMOLECULAR MATERIAL CO LTD | 2013-10-02 | — | — | CN | claimed |
| CN-103242635-A | Permanent antistatic polycarbonate composite and preparation method thereof | SHANGYU JAVA MACROMOLECULAR MATERIAL CO LTD | 2013-08-14 | — | — | CN | claimed |
| WO-2003101967-A1 | PREPARATION OF CHIRAL 1,2,3,4-TETRAHYDRO-6,7-DIALKOXY-3-ISOQUINOLINECARBOXYLIC ACID AND DERIVATIVES BY REACTING LEVODOPA WITH FORMALDEHYDE OR FORMALDEHYDE PRECURSORS | APTEX PHARMACHEM INC. (CA) | 2003-12-11 | — | — | WO | claimed |
| US-6642384-B1 | Forming intermediate to moexipril; cyclizing levodopa with formaldehyde; protecting amine, alkylating phenols, esterifying carboxylic acid and optionally deprotecting | BRANTFORD CHEMICALS INC. (CA) | 2003-11-04 | — | — | US | claimed |
| US-6586599-B1 | Formating carbon-carbon bonds between carbocyclic halogen and organosilicon compounds in the presence of coordination catalysts, nitrogen compounds and bases; efficiency; catalysis | UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION | 2003-07-01 | — | — | US | claimed |
| US-6403801-B1 | MIXING IN LIQUID MEDIUM STRONG BASE, ARYL HALIDE OR ARYL PSEUDOHALIDE, ARYLBORONIC ACID, NICKEL, PALLADIUM OR PLATINUM COMPOUND, N-HETEROCYCLIC CARBENE SELECTED FROM IMIDAZOLINE-2-YLIDENE, BIS(IMIDAZOLINE-2-YLIDENE) OR SALTS | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION | 2002-06-11 | — | — | US | claimed |
| US-6403802-B1 | MIXING IN LIQUID MEDIUM STRONG BASE, ARYL HALIDE OR ARYL PSEUDOHALIDE, PRIMARY AND/OR SECONDARY AMINE, NICKEL, PALLADIUM OR PLATINUM COMPOUND, N-HETEROCYCLIC CARBENE SUCH AS IMIDAZOLINE-2-YLIDENE, BIS(IMIDAZOLINE-2-YLIDENE) OR SALTS | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION | 2002-06-11 | — | — | US | claimed |
| US-6369265-B1 | HETEROCOUPLING REACTION, MIXING IN A LIQUID AN ARYL HALIDE, BONDING TO AROMATIC RINGS, GRIGNARD REACTION, METAL COMPOUND AND HETEROCYCLIC CARBENE | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION | 2002-04-09 | — | — | US | claimed |
| US-6362357-B1 | PHOSPHINE; USING ARYL HALIDES; ORGANOTIN COMPOUNDS | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION | 2002-03-26 | — | — | US | claimed |
| WO-2001066248-A2 | C-C AND C-N COUPLING CATALYST COMPRISING TRANSITION METAL AND CARBENE | UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION (US) | 2001-09-13 | — | — | WO | claimed |
| US-5602228-A | Nickel phosphate catalysts | MAXDEM INCORPORATED (US) | 1997-02-11 | — | — | US | claimed |
| WO-1996039455-A1 | NICKEL PHOSPHITE CATALYSTS | MAXDEM INCORPORATED (US) | 1996-12-12 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220056054-A1 | METHODS OF PREPARATION OF AMINOBORANES AND APPLICATIONS FOR BORYLATION AND SUZUKI COUPLING | BLVRB, ALKBH2, CBR1 | MCHR1 166/4885RECQL 2876/4885TSHR 76/4885 |
| US-20160229778-A1 | DIRECT B-ARYLATION OF CARBONYL COMPOUNDS | DBH, DDT, CBR3 | MCHR1 3410/4885RECQL 4641/4885TSHR 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.