Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 2/20 | 0.56 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23111396 | 0.79 | SLC22A2 (0.50) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL1200520 | 0.77 | SLC22A2 (0.62) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| Rimantadine SCHEMBL2982 | 0.72 | SLC22A2 (1.00) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL40513 | 0.72 | SLC22A2 (0.56) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| Rimantadine SCHEMBL15532385 | 0.72 | SLC22A2 (1.00) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL27514830 | 0.72 | SLC22A2 (0.44) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| Rimantadine SCHEMBL2981 | 0.72 | SLC22A2 (1.00) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| Rimantadine SCHEMBL20409367 | 0.72 | SLC22A2 (1.00) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL821156 | 0.72 | SLC22A2 (0.50) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| Rimantadine SCHEMBL4366035 | 0.70 | MAPT (1.00) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880154-A | MALEIC ANHYDRIDE-DIVINYL ETHER MODIFIED WITH AMINOALKYLENEADMANTANE OR HYDROXYALKYLENEADMATANE DERIVATIVE AND THEN HYDROLYZED; USED AS ANTIVIRAL AGAINST HIV-1 | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1999-03-09 | — | — | US | disclosed |
| WO-1995020951-A1 | POLYMERIC ADAMANTANE ANALOGUES | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1995-08-10 | — | — | WO | disclosed |